• DRAMP ID

    • DRAMP00231
    • Peptide Name

    • Lariatins B (lasso peptide; Bacteriocin)
    • Source

    • Rhodococcus jostii K01-B0171 (Gram-positive bacteria)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • GSQLVYREWVGHSNVIKGPP
    • Sequence Length

    • 20
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

      • Gram-positive bacteria: Mycobacterium smegmatis and Mycobacterium tuberculosis.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00231 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP00231.
    • Formula

    • C101H155N29O28
    • Absent Amino Acids

    • ACDFMT
    • Common Amino Acids

    • GV
    • Mass

    • 2223.52
    • PI

    • 8.6
    • Basic Residues

    • 3
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 6
    • Net Charge

    • +2
    • Boman Index

    • -23.95
    • Hydrophobicity

    • -0.47
    • Aliphatic Index

    • 82.5
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 6990
    • Absorbance 280nm

    • 367.89
    • Polar Residues

    • 7

DRAMP00231

DRAMP00231 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure.
    • Reference

    • J Am Chem Soc. 2006 Jun 14;128(23):7486-7891.
    • Author

    • Iwatsuki M, Tomoda H, Uchida R, Gouda H, Hirono S, Omura S.