General Information

    • DRAMP ID

    • DRAMP00251

    • Peptide Name

    • Bacteriocin serracin-P 23 kDa subunit (Bacteriocin)

    • Source

    • Serratia plymuthica J7 (Gram-negative bacteria)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ALPKKLKYLNLFNDGFNYMGVV

    • Sequence Length

    • 22

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-

    • Target Organism

      • Gram-negative bacterium: Erwinia amylovora.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00251 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00251.

Physicochemical Information

    • Formula

    • C121H186N28O30S

    • Absent Amino Acids

    • CEHIQRSTW

    • Common Amino Acids

    • L

    • Mass

    • 2545.04

    • PI

    • 9.41

    • Basic Residues

    • 3

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +2

    • Boman Index

    • -5.81

    • Hydrophobicity

    • 0.1

    • Aliphatic Index

    • 101.82

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 2980

    • Absorbance 280nm

    • 141.9

    • Polar Residues

    • 7

DRAMP00251

DRAMP00251 chydropathy plot

Comments Information

    • Function

    • Major component of a prophage tail tube. Antibacterial activity against Gram-negative bacteria E.amylovora.

Literature Information

  • ·Literature 1

    • Title

    • Characterization of serracin P, a phage-tail-like bacteriocin, and its activity against Erwinia amylovora, the fire blight pathogen.

    • Reference

    • Appl Environ Microbiol. 2002 Nov;68(11):5704-5710.

    • Author

    • Jabrane A, Sabri A, Comp¨re P, Jacques P, Vandenberghe I, Van Beeumen J, Thonart P.