General Information

    • DRAMP ID

    • DRAMP00312

    • Peptide Name

    • Endochitinase 2 (Plant defensin)

    • Source

    • Taxus baccata (English yew)

    • Family

    • Belongs to the glycosyl hydrolase 28 family (Chitinase class I subfamily)

    • Gene

    • Not found

    • Sequence

    • TAGFGVFTNIINGGLECGK

    • Sequence Length

    • 19

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00312 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00312.

Physicochemical Information

    • Formula

    • C84H132N22O26S

    • Absent Amino Acids

    • DHMPQRSWY

    • Common Amino Acids

    • G

    • Mass

    • 1898.16

    • PI

    • 5.66

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 7

    • Net Charge

    • 0

    • Boman Index

    • 1.77

    • Hydrophobicity

    • 0.479

    • Aliphatic Index

    • 82.11

    • Half Life

      • Mammalian:7.2 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 10

DRAMP00312

DRAMP00312 chydropathy plot

Comments Information

    • Function

    • Defense against chitin containing fungal pathogens.

    • Catalytic activity

    • Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

    • PTM

    • Contians one disulfide bond (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Analysis of the soluble cell wall proteome of gymnosperms.

    • Reference

    • J Plant Physiol. 2009 May 15;166(8):831-843.

    • Author

    • Uzal EN, Gómez-Ros LV, Hernández JA, Pedreño MA, Cuello J, Ros Barceló A.