General Information

    • DRAMP ID

    • DRAMP00318

    • Peptide Name

    • Endochitinase B (Plant defensin)

    • Source

    • Pisum sativum (Garden pea)

    • Family

    • Belongs to the glycosyl hydrolase 34 family (Chitinase class I subfamily)

    • Gene

    • Not found

    • Sequence

    • EQCGRQAGGATCPNNLCCSQYGY

    • Sequence Length

    • 23

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Chitin-binding

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00318 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00318.

Physicochemical Information

    • Formula

    • C96H147N31O35S4

    • Absent Amino Acids

    • DFHIKMVW

    • Common Amino Acids

    • CG

    • Mass

    • 2423.65

    • PI

    • 6.06

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 3

    • Net Charge

    • 0

    • Boman Index

    • -40.46

    • Hydrophobicity

    • -0.67

    • Aliphatic Index

    • 25.65

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 3230

    • Absorbance 280nm

    • 146.82

    • Polar Residues

    • 14

DRAMP00318

DRAMP00318 chydropathy plot

Comments Information

    • Function

    • Defense against chitin containing fungal pathogens.

    • Catalytic activity

    • Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

    • Induction

    • By infection with the fungal pathogen Ascochyta pisi.

Literature Information

  • ·Literature 1

    • Title

    • Induction, purification and characterization of chitinase isolated from pea leaves inoculated with Ascochyta pisi.

    • Reference

    • Planta 184:24-29(1991).

    • Author

    • Vad K, Mikkelsen JD, Collinge DB.