• DRAMP ID

    • DRAMP00384
    • Peptide Name

    • Cc-GRP (Gly-rich; Plants)
    • Source

    • Coffea canephora
    • Family

    • Unknow
    • Gene

    • Unknow
    • Sequence

    • GNEGGGHGGHGGYGGYHHHGGGGGGYGGYHGGGGS
    • Sequence Length

    • 35
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknow
    • Biological Activity

    • Antifungal
    • Target Organism

      • Fungi: Candida albicans (MIC=90 µg/ml), Candida tropicalis (MIC=180 µg/ml), Colletotrichum lindemuthianum (MIC=90 µg/ml), Fusarium oxysporium (MIC=90 µg/ml).
    • Hemolytic activity

    • Unknown
    • Binding Traget

    • Unknow
    • Structure

    • Rich
    • Structure Description

    • Unknow
    • PDB ID

    • Unknow
    • DRAMP00384 helical wheel diagram
    • Formula

    • C128H164N48O44
    • Absent Amino Acids

    • ACDFIKLMPQRTVW
    • Common Amino Acids

    • G
    • Mass

    • 3685.66
    • PI

    • 7.18
    • Basic Residues

    • 6
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 0
    • Boman Index

    • -24.69
    • Hydrophobicity

    • -117.14
    • Aliphatic Index

    • 0
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5960
    • Absorbance 280nm

    • 175.29
    • Polar Residues

    • 28

Amino Acid Distribution

DRAMP00384 chydropathy plot
    • The sequence displayed is only the N-terminal sequence of 7 kD peptide. The peptide was located in the cell wall, cell surface and nucleus of Fusarium oxysporum.

  • Literature 1
    • Reference

    • Biochim Biophys Acta. 2013 Mar 15.[Epub ahead of print]
    • Author

    • Zottich U, Da Cunha M, Carvalho AO, Dias GB, Casarin N, Vasconcelos IM, Gomes VM.
    • Title

    • An antifungal peptide from Coffea canephora seeds with sequence homology to glycine-rich proteins exerts membrane permeabilization and nuclear localization in fungi.