General Information
-
DRAMP ID
- DRAMP00402
-
Peptide Name
- Defensin D1 (So-D1; Antimicrobial peptide D1; Plant defensin)
-
Source
- Spinacia oleracea (Spinach)
-
Family
- Belongs to the DEFL family
-
Gene
- Not found
-
Sequence
- XTCESPSHKFKGPCATNRNCES
-
Sequence Length
- 22
-
UniProt Entry
- P81572
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
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Target Organism
-
- Gram-positive bacterium: Clavibacter michiganensis;
- Gram-negative bacterium: Ralstonia solanacearum.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00402.
Physicochemical Information
-
Formula
- C92H144N30O32S3
Absent Amino Acids
- DILMQVWY
Common Amino Acids
- CS
Mass
- 2407.86
PI
- 7.96
Basic Residues
- 4
Acidic Residues
- 2
Hydrophobic Residues
- 2
Net Charge
- +2
-
Boman Index
- -63.35
Hydrophobicity
- -1.127
Aliphatic Index
- 4.55
Half Life
-
- Mammalian:?
- Yeast:?
- E.coli:?
Extinction Coefficient Cystines
- 125
Absorbance 280nm
- 5.95
Polar Residues
- 11
DRAMP00402
Comments Information
Function
- Antimicrobial peptide. Active against Gram-positive and Gram-negative bacterial pathogens.
Literature Information
- ·Literature 1
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Title
- Novel defensin subfamily from spinach (Spinacia oleracea).
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Pubmed ID
- 9762899
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Reference
- FEBS Lett. 1998; 435: 159-162.
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Author
- Segura A, Moreno M, Molina A, Garca-Olmedo F.