• DRAMP ID

    • DRAMP00411
    • Peptide Name

    • Defensin-like protein 2 (Bn-AFP2; Plant defensin)
    • Source

    • Brassica napus (Rape)
    • Family

    • Belongs to the DEFL family
    • Gene

    • Not found
    • Sequence

    • QKLCERPSGTWSGVCGNNNACKN
    • Sequence Length

    • 23
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antifungal
    • Target Organism

      • Fungi: Alternaria brassicola (IC50=75 µg/ml), Botrytis cinerea(IC50> 100 µg/ml), Fusarium culmorum (IC50=38 µg/ml), Fusarium oxysporum f.sp.lycopersici (IC50=42 µg/ml), Pyricularia oryzae (IC50=3 µg/ml), Verticiliium dahliae (IC50=15 µg/ml).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Rich
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00411 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP00411.
    • Formula

    • C99H160N34O34S3
    • Absent Amino Acids

    • DFHIMY
    • Common Amino Acids

    • N
    • Mass

    • 2466.75
    • PI

    • 8.68
    • Basic Residues

    • 3
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 4
    • Net Charge

    • +2
    • Boman Index

    • -54.54
    • Hydrophobicity

    • -0.957
    • Aliphatic Index

    • 33.91
    • Half Life

      • Mammalian:0.8 hour
      • Yeast:10 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5625
    • Absorbance 280nm

    • 255.68
    • Polar Residues

    • 13

DRAMP00411

DRAMP00411 chydropathy plot
    • Function

    • Possesses antifungal activity sensitive to inorganic cations.
    • Subunit structure

    • Forms oligomers in its native state.
  • ·Literature 1
    • Title

    • A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
    • Reference

    • FEBS Lett. 1993 Feb 1;316(3):233-240.
    • Author

    • Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.