• DRAMP ID

    • DRAMP00437
    • Peptide Name

    • Pisum sativum defensin 2 (Psd2; Plant defensin)
    • Source

    • Pisum sativum (Garden pea)
    • Family

    • Belongs to the DEFL family
    • Gene

    • Unknow
    • Sequence

    • KTCENLSGTFKGPCIPDGNCNKHCRNNEHLLSGRCRDDFRCWCTNRC
    • Sequence Length

    • 47
    • Evidence code

    • Protein level
    • Biological Activity

    • Antifungal
    • Target Organism

      • PD: Aspergillus niger (MIC=10.2 µg/ml), Aspergillus versicolor (MIC=0.34 µg/ml), Fusarium moniliforme (MIC=10.0 µg/ml), Fusarium oxysporum (MIC>100 µg/ml), Fusarium solani (MIC=8.5 µg/ml), Neurospora crassa (MIC<0.5 µg/ml), Saccharomyces cerevisae (MIC>100 µg/ml), Trichophyton mentagrophytes (MIC<100 µg/ml).
      • PD+: Aspergillus niger (MIC=7.8 µg/ml), Aspergillus versicolor (MIC=5.9 µg/ml), Fusarium moniliforme (MIC=25 µg/ml), Fusarium oxysporum (MIC>100 µg/ml), Fusarium solani (MIC=5.0 µg/ml).
      • NOTE: PD+ = potato dextrose medium supplemented with 1 mM CaCl2.
    • Hemolytic activity

    • Unknown
    • Binding Traget

    • Unknow
    • Structure

    • Bridge
    • Structure Description

    • Unknow
    • PDB ID

    • Unknow
    • DRAMP00437 helical wheel diagram
    • Formula

    • C219H346N76O69S8
    • Absent Amino Acids

    • AMQVY
    • Common Amino Acids

    • C
    • Mass

    • 6224.79
    • PI

    • 8.22
    • Basic Residues

    • 10
    • Acidic Residues

    • 5
    • Hydrophobic Residues

    • 7
    • Boman Index

    • -152.73
    • Hydrophobicity

    • -100
    • Aliphatic Index

    • 33.19
    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 6000
    • Absorbance 280nm

    • 130.43
    • Polar Residues

    • 23

DRAMP00437

DRAMP00437 chydropathy plot
    • PTM

    • Contains four disulfide bonds 3-47; 14-35; 20-41; 24-43.
  • Literature 1
    • Reference

    • Arch Biochem Biophys. 2000 Jun 15;378(2):278-286.
    • Author

    • Almeida M.S, Cabral K.M, Zingali R.B, Kurtenbach E.
    • Title

    • Characterization of two novel defense peptides from pea (Pisum sativum) seeds.