• DRAMP ID

    • DRAMP00766
    • Peptide Name

    • JCpep7 (Plants)
    • Source

    • Jatropha curcas
    • Family

    • Unknow
    • Gene

    • Unknow
    • Sequence

    • KVFLGLK
    • Sequence Length

    • 7
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknow
    • Biological Activity

    • Unkonw
    • Target Organism

      • Gram-negative bacteria: Salmonella typhimurium ATCC 50013 (MIC=48 µg/ml), Shigella dysenteriae ATCC 51302 (MIC=48 µg/ml), Pseudomonas aeruginosa ATCC 27553 (MIC=64 µg/ml);
      • Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=40 µg/ml), Bacillus subtilis ATCC 23631 (MIC=24 µg/ml), Streptococcus pneumoniae ATCC 49619 (MIC=56 µg/ml).
    • Hemolytic activity

    • Unknown
    • Binding Traget

    • Unknow
    • Structure

    • Unknow
    • Structure Description

    • Unknow
    • PDB ID

    • Unknow
    • DRAMP00766 helical wheel diagram
    • Formula

    • C40H69N9O8
    • Absent Amino Acids

    • ACDEHIMNPQRSTWY
    • Common Amino Acids

    • KL
    • Mass

    • 911.25
    • PI

    • 10.81
    • Basic Residues

    • 2
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 4
    • Boman Index

    • 6.7
    • Hydrophobicity

    • 91.43
    • Aliphatic Index

    • 152.86
    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 1

DRAMP00766

    • Function

    • JCpep7 killed microbes principally via breaking of their cell walls and membranes, followed by cell lysis.
  • Literature 1
    • Reference

    • J Agric Food Chem. 2011 Feb 23;59(4):1145-1151.
    • Author

    • Xiao J, Zhang H, Niu L, Wang X.
    • Title

    • Efficient Screening of a Novel Antimicrobial Peptide from Jatropha curcas by Cell Membrane Affinity Chromatography.