General Information

    • DRAMP ID

    • DRAMP01065

    • Peptide Name

    • Chitin-binding protein HM30 (Plants)

    • Source

    • Hydrangea macrophylla (Bigleaf hydrangea)

    • Family

    • Belongs to the parathyroid hormone family

    • Gene

    • Not found

    • Sequence

    • NSMERVEELRKKLQD

    • Sequence Length

    • 15

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Alternria alternate, Alternaria cucumerina, Aspergillus niger, Collectotrichum gossypii, Fusarium oxysporum, F. oxysporum subsp melonis, Fusarium moniliforme, Thanatephorus cucumeris, Verticillium dahliae, Pyricularia oryzae Cav..

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Chitin-binding

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01065 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01065.

Physicochemical Information

    • Formula

    • C77H135N25O27S

    • Absent Amino Acids

    • ACFGHIPTWY

    • Common Amino Acids

    • E

    • Mass

    • 1875.13

    • PI

    • 6.26

    • Basic Residues

    • 4

    • Acidic Residues

    • 4

    • Hydrophobic Residues

    • 3

    • Net Charge

    • 0

    • Boman Index

    • -69.44

    • Hydrophobicity

    • -1.66

    • Aliphatic Index

    • 71.33

    • Half Life

      • Mammalian:1.4 hour
      • Yeast:3 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 2

DRAMP01065

Comments Information

    • Function

    • Has antifungal activity against phytopathogenic fungi. Has no chitinase or agglutination activities.

Literature Information

  • ·Literature 1

    • Title

    • Purification and characterization of an ethylene-induced antifungal protein from leaves of Guilder rose (Hydrangea macrophylla).

    • Reference

    • Protein Expr Purif. 2002 Feb;24(1):76-82.

    • Author

    • Yang Q, Gong ZZ.