General Information

    • DRAMP ID

    • DRAMP01178

    • Peptide Name

    • Ocellatin-K1 (Frogs, amphibians, animals)

    • Source

    • Leptodactylus knudseni (Knudsen's thin-toed frog) (Amazonian toad-frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GVVDILKGAAKDLAGHLASKVMNKI

    • Sequence Length

    • 25

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • [Swiss_Prot Entry P86711]show antibacterial activity

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01178 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01178.

Physicochemical Information

    • Formula

    • C113H198N32O32S

    • Absent Amino Acids

    • CEFPQRTWY

    • Common Amino Acids

    • AK

    • Mass

    • 2549.07

    • PI

    • 9.53

    • Basic Residues

    • 5

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +3

    • Boman Index

    • -5.21

    • Hydrophobicity

    • 0.432

    • Aliphatic Index

    • 128.8

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP01178

DRAMP01178 chydropathy plot

Comments Information

    • Function

    • Has antibacterial activity. Tissue specificity

Literature Information

  • ·Literature 1

    • Title

    • Identification of peptides from Amazonian Leptodactylus knudseni skin secretion by MALDI TOF/TOF.

    • Reference

    • Submitted (JUL-2010) to UniProtKB

    • Author

    • Cardozo-Filho J.L, Soares A.A, Bloch C. Jr, Silva L.P, Stabeli R.G, Calderon L.A.