General Information
-
DRAMP ID
- DRAMP01321
-
Peptide Name
- Amolopin-n1 antimicrobial peptide (Frogs, amphibians, animals)
-
Source
- Amolops loloensis (Rufous-spotted torrent frog)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- MFTLKKSLLLLFFLGTINLSLCEQERNAEEERRDDLGERQAEVEKRFFPIVGKLLSG
-
Sequence Length
- 57
-
UniProt Entry
- C5H0E2
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial
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Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01321.
Physicochemical Information
-
Formula
- C297H482N80O87S2
Absent Amino Acids
- HWY
Common Amino Acids
- L
Mass
- 6629.7
PI
- 5.34
Basic Residues
- 9
Acidic Residues
- 10
Hydrophobic Residues
- 22
Net Charge
- -1
-
Boman Index
- -110.47
Hydrophobicity
- -0.226
Aliphatic Index
- 102.63
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 12
DRAMP01321
Comments Information
Function
- Amphibian defense peptide.
Literature Information
- ·Literature 1
-
Title
- Five novel antimicrobial peptides from skin secretions of the frog, Amolops loloensis.
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Pubmed ID
- 19843479
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Reference
- Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan;155(1):72-76.
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Author
- Wang M, Wang Y, Wang A, Song Y, Ma D, Yang H, Ma Y, Lai R.