General Information
-
DRAMP ID
- DRAMP01344
-
Peptide Name
- Amolopin-2c (Frogs, amphibians, animals)
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Source
- Amolops loloensis (Rufous-spotted torrent frog)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- LLPIVGKLLSGLL
-
Sequence Length
- 13
-
UniProt Entry
- A0SN50
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
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Target Organism
-
- Gram-positive bacteria: Staphylococcus aureus, Bacillus dysenteriae;
- Gram-negative bacterium: Escherichia coli.
- Yeast: Candida albicans.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01344.
Physicochemical Information
-
Formula
- C65H118N14O15
Absent Amino Acids
- ACDEFHMNQRTWY
Common Amino Acids
- L
Mass
- 1335.74
PI
- 8.75
Basic Residues
- 1
Acidic Residues
- 0
Hydrophobic Residues
- 8
Net Charge
- +1
-
Boman Index
- 31.41
Hydrophobicity
- 1.877
Aliphatic Index
- 232.31
Half Life
-
- Mammalian:5.5 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 3
DRAMP01344
Comments Information
Function
- Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Literature Information
- ·Literature 1
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Title
- Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis
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Pubmed ID
- 17000029
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Reference
- Peptides 2006; 27: 3085-3091.
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Author
- Lu Y et al Lai R2006