General Information

    • DRAMP ID

    • DRAMP01425

    • Peptide Name

    • Nigrocin-OG21 (frog, amphibians, animals)

    • Source

    • Odorrana grahami (Yunnanfu frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GLLSGVLGVGKKVDCGLSGLC

    • Sequence Length

    • 21

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01425 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01425.

Physicochemical Information

    • Formula

    • C85H151N23O26S2

    • Absent Amino Acids

    • AEFHIMNPQRTWY

    • Common Amino Acids

    • G

    • Mass

    • 1975.39

    • PI

    • 8.05

    • Basic Residues

    • 2

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +1

    • Boman Index

    • 18.3

    • Hydrophobicity

    • 1.014

    • Aliphatic Index

    • 134.29

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 6.25

    • Polar Residues

    • 10

DRAMP01425

DRAMP01425 chydropathy plot

Comments Information

    • Function

    • Showes an effect on HIV when applied in combination with OdK1.

Literature Information

  • ·Literature 1

    • Title

    • Anti-infection peptidomics of amphibian skin.

    • Reference

    • Mol Cell Proteomics. 2007 May;6(5):882-894.

    • Author

    • Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J.