General Information

    • DRAMP ID

    • DRAMP01654

    • Peptide Name

    • Dermaseptin-B8 (Frogs, amphibians, animals)

    • Source

    • Phyllomedusa bicolor (Two-colored leaf frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GLWSKIKEAGKAVLTAAGKAALGAVSDAV

    • Sequence Length

    • 29

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Antiviral

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01654 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01654.

Physicochemical Information

    • Formula

    • C125H212N34O37

    • Absent Amino Acids

    • CFHMNPQRY

    • Common Amino Acids

    • A

    • Mass

    • 2783.26

    • PI

    • 9.53

    • Basic Residues

    • 4

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 16

    • Net Charge

    • +2

    • Boman Index

    • 5.27

    • Hydrophobicity

    • 0.535

    • Aliphatic Index

    • 111.38

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 196.43

    • Polar Residues

    • 7

DRAMP01654

DRAMP01654 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Structure of genes for dermaseptins B, antimicrobial peptides from frog skin. Exon 1-encoded prepropeptide is conserved in genes for peptides of highly different structures and activities.

    • Reference

    • FEBS Lett. 1997 Sep 1;414(1):27-32.

    • Author

    • Vouille V, Amiche M, Nicolas P.