General Information

    • DRAMP ID

    • DRAMP01681

    • Peptide Name

    • Dermaseptin-S6 (DS6; Frogs, amphibians, animals)

    • Source

    • Phyllomedusa sauvagei (Sauvage's leaf frog)

    • Family

    • Belongs to the frog skin active peptide family (Dermaseptin subfamily)

    • Gene

    • Not found

    • Sequence

    • GLWSKIKTAGKEAAKAAAKAAGKAALNAVSEAI

    • Sequence Length

    • 33

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01681 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01681.

Physicochemical Information

    • Formula

    • C142H243N41O42

    • Absent Amino Acids

    • CDFHMPQRY

    • Common Amino Acids

    • A

    • Mass

    • 3196.74

    • PI

    • 10

    • Basic Residues

    • 6

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 18

    • Net Charge

    • +4

    • Boman Index

    • -12.34

    • Hydrophobicity

    • 0.124

    • Aliphatic Index

    • 92.42

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 171.88

    • Polar Residues

    • 7

DRAMP01681

DRAMP01681 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Kinestatin: a novel bradykinin B2 receptor antagonist peptide from the skin secretion of the Chinese toad, Bombina maxima.

    • Reference

    • Regul Pept. 2003 Nov 15;116(1-3):147-154.

    • Author

    • Chen T, O'Rourke M, Orr DF, Coulter DJ, Hirst DG, Rao P, Shaw C.