• DRAMP ID

    • DRAMP01689
    • Peptide Name

    • Dermaseptin AA-3-4 (Frogs, amphibians, animals)
    • Source

    • Agalychnis annae (Blue-sided leaf frog)
    • Family

    • Belongs to the frog skin active peptide family (Dermaseptin subfamily)
    • Gene

    • Not found
    • Sequence

    • GMWGSLLKGVATVVKHVLPHALSSQQS
    • Sequence Length

    • 27
    • Protein Existence

    • Transcript level
    • Biological Activity

    • Antimicrobial, Antibacterial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01689 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01689.
    • Formula

    • C127H208N36O35S
    • Absent Amino Acids

    • CDEFINRY
    • Common Amino Acids

    • LSV
    • Mass

    • 2831.33
    • PI

    • 10
    • Basic Residues

    • 4
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 11
    • Net Charge

    • +4
    • Boman Index

    • -0.71
    • Hydrophobicity

    • 0.322
    • Aliphatic Index

    • 108.15
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5500
    • Absorbance 280nm

    • 211.54
    • Polar Residues

    • 8

DRAMP01689

DRAMP01689 chydropathy plot
    • MOA

    • Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).
  • ·Literature 1
    • Title

    • Cloning of cDNAs encoding new peptides of the dermaseptin-family.
    • Reference

    • Biochim Biophys Acta. 1998 Oct 14;1388(1):279-283.
    • Author

    • Wechselberger C.