General Information

    • DRAMP ID

    • DRAMP01762

    • Peptide Name

    • Temporin-PRb (Frogs, amphibians, animals)

    • Source

    • Rana pretiosa (Oregon spotted frog)

    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)

    • Gene

    • Not found

    • Sequence

    • FLPIITNLLGKLL

    • Sequence Length

    • 13

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01762 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01762.

Physicochemical Information

    • Formula

    • C72H123N15O16

    • Absent Amino Acids

    • ACDEHMQRSVWY

    • Common Amino Acids

    • L

    • Mass

    • 1454.86

    • PI

    • 8.75

    • Basic Residues

    • 1

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +1

    • Boman Index

    • 23.6

    • Hydrophobicity

    • 1.592

    • Aliphatic Index

    • 210

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 3

DRAMP01762

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Host defense peptides in skin secretions of the Oregon spotted frog Ranapretiosa: implications for species resistance to chytridiomycosis.

    • Reference

    • Dev Comp Immunol. 2011 Jun;35(6):644-649.

    • Author

    • Conlon JM, Mechkarska M, Emanahmed, Coquet L, Jouenne T, Jérômeleprince, Vaudry H, Hayes MP, Padgett-Flohr G.