• DRAMP ID

    • DRAMP01810
    • Peptide Name

    • Temporin-1BYa (Frogs, amphibians, animals)
    • Source

    • Rana boylii (Foothill yellow-legged frog)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • FLPIIAKVLSGLL
    • Sequence Length

    • 13
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

      • Gram-positive bacterium: Staphylococcus aureus.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01810 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01810.
    • Formula

    • C69H118N14O15
    • Absent Amino Acids

    • CDEHMNQRTWY
    • Common Amino Acids

    • L
    • Mass

    • 1383.78
    • PI

    • 8.75
    • Basic Residues

    • 1
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 9
    • Net Charge

    • +1
    • Boman Index

    • 30.34
    • Hydrophobicity

    • 2.023
    • Aliphatic Index

    • 210
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 2

DRAMP01810

    • Function

    • Antibacterial activity against the Gram-positive bacteria
  • ·Literature 1
    • Title

    • Isolation of peptides of the brevinin-3 family with potent candidacidal activity from the skin secretions of the frog Rana boylii.
    • Reference

    • J Pept Res. 2003 Nov;62(5):207-213.
    • Author

    • Conlon JM, Sonnevend A, Patel M, Davidson C, Nielsen PF, Pál T, Rollins-Smith LA.