• DRAMP ID

    • DRAMP01946
    • Peptide Name

    • Brevinin-20a (Frogs, amphibians, animals)
    • Source

    • Rana Ornativentris (Japanese mountain brown frog)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • GLFNVFKGLKTAGKHVAGSLLNQLKCKVSGGC
    • Sequence Length

    • 32
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
    • Target Organism

      • Gram-positive bacterium: Staphylococcus aureus;
      • Gram-negative bacterium: Escherichia coli.
      • Yeast: Candida albicans.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01946 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01946.
    • Formula

    • C146H244N42O39S2
    • Absent Amino Acids

    • DEIMPRWY
    • Common Amino Acids

    • G
    • Mass

    • 3275.92
    • PI

    • 9.9
    • Basic Residues

    • 6
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +6
    • Boman Index

    • -6.1
    • Hydrophobicity

    • 0.247
    • Aliphatic Index

    • 94.38
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 4.03
    • Polar Residues

    • 13

DRAMP01946

DRAMP01946 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Antimicrobial peptides from the skin of the Japanese mountain brown frog, Rana ornativentris.
    • Reference

    • J Pept Res. 2001 Nov;58(5):349-356.
    • Author

    • Kim JB et al Conlon JM.