General Information

    • DRAMP ID

    • DRAMP01947

    • Peptide Name

    • Brevinin-20b (Frogs, amphibians, animals)

    • Source

    • Rana Ornativentris (Japanese mountain brown frog)

    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)

    • Gene

    • Not found

    • Sequence

    • GIFNVFKGALKTAGKHVAGSLLNQLKCKVSGEC

    • Sequence Length

    • 33

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

    • Target Organism

      • Gram-positive bacterium: Staphylococcus aureus;
      • Gram-negative bacterium: Escherichia coli.
      • Yeast: Candida albicans.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01947 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01947.

Physicochemical Information

    • Formula

    • C152H253N43O42S2

    • Absent Amino Acids

    • DMPRWY

    • Common Amino Acids

    • GK

    • Mass

    • 3419.06

    • PI

    • 9.6

    • Basic Residues

    • 6

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 13

    • Net Charge

    • +5

    • Boman Index

    • -12.04

    • Hydrophobicity

    • 0.221

    • Aliphatic Index

    • 94.55

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 3.91

    • Polar Residues

    • 12

DRAMP01947

DRAMP01947 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial peptides from the skin of the Japanese mountain brown frog, Rana ornativentris.

    • Reference

    • J Pept Res. 2001 Nov;58(5):349-356.

    • Author

    • Kim JB et al Conlon JM.