General Information

    • DRAMP ID

    • DRAMP02079

    • Peptide Name

    • Brevinin-1AVa (Frogs, amphibians, animals)

    • Source

    • Rana arvalis (Moor frog)

    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)

    • Gene

    • Not found

    • Sequence

    • FLPLLAASFACTVTKKC

    • Sequence Length

    • 17

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02079 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02079.

Physicochemical Information

    • Formula

    • C84H137N19O21S2

    • Absent Amino Acids

    • DEGHIMNQRWY

    • Common Amino Acids

    • AL

    • Mass

    • 1813.25

    • PI

    • 8.9

    • Basic Residues

    • 2

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +2

    • Boman Index

    • 13.11

    • Hydrophobicity

    • 1.177

    • Aliphatic Index

    • 103.53

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 7.81

    • Polar Residues

    • 5

DRAMP02079

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Oxidation versus carboxamidomethylation of S-S bond in ranid frog peptides: pro and contra for de novo MALDI-MS sequencing.

    • Reference

    • J Am Soc Mass Spectrom. 2008 Apr;19(4):479-487.

    • Author

    • Samgina TY, Artemenko KA, Gorshkov VA, Poljakov NB, Lebedev AT.
  • ·Literature 2

    • Title

    • Mass spectrometric study of peptides secreted by the skin glands of the brown frog Rana arvalis from the Moscow region.

    • Reference

    • Rapid Commun Mass Spectrom. 2009 May;23(9):1241-1248.

    • Author

    • Samgina TY, Artemenko KA, Gorshkov VA, Ogourtsov SV, Zubarev RA, Lebedev AT.