• DRAMP ID

    • DRAMP02154
    • Peptide Name

    • Hemolytic protein B9 (Frogs, amphibians, animals)
    • Source

    • Rana esculenta (Edible frog) (Pelophylax esculentus)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • FLPLIAGLLGKLF
    • Sequence Length

    • 13
    • Protein Existence

    • Protein level
    • Biological Activity

    • Unknown
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • [Ref.11738090]4% hemolytic activity at 1 nmol/ml, 5% hemolytic activity at 1.5nmol/ml, 17% hemolytic activity at 2nmol/ml, 20% hemolytic activity at 2.5nmol/ml, 35% hemolytic activity at 3nmol/ml, 90% hemolytic activity at 3.5nmol/ml against human erythrocytes
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02154 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02154.
    • Formula

    • C72H116N14O14
    • Absent Amino Acids

    • CDEHMNQRSTVWY
    • Common Amino Acids

    • L
    • Mass

    • 1401.8
    • PI

    • 8.75
    • Basic Residues

    • 1
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 9
    • Net Charge

    • +1
    • Boman Index

    • 33.62
    • Hydrophobicity

    • 1.892
    • Aliphatic Index

    • 187.69
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 2

DRAMP02154

    • Function

    • Shows hemolytic activity.
    • Tissue specificity

    • Expressed by the skin glands.
  • ·Literature 1
    • Title

    • Purification and characterization of bioactive peptides from skin extracts of Rana esculenta.
    • Reference

    • Biochim Biophys Acta. 1990 Mar 26;1033(3):318-323.
    • Author

    • Simmaco M, De Biase D, Severini C, Aita M, Erspamer GF, Barra D, Bossa F.