General Information

    • DRAMP ID

    • DRAMP02932

    • Peptide Name

    • GRPSp (crabs, Arthropods, animals)

    • Source

    • Scylla paramamosain (Mud crab)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • IPAMEPAARVKRSPGYGGCSPRWACGGYG

    • Sequence Length

    • 29

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+

    • Target Organism

      • Gram-positive bacteria: Staphylococcus haemolyticus (MIC>50 µM), Aerococcus viridans (MIC=6.25-12.5 µM), Micrococcus luteus (MIC=12.5-25 µM), Bacillus subtilis (MIC>50 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02932 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02932.

Physicochemical Information

    • Formula

    • C130H200N40O36S3

    • Absent Amino Acids

    • DFHLNQT

    • Common Amino Acids

    • G

    • Mass

    • 2995.44

    • PI

    • 9.39

    • Basic Residues

    • 4

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 7

    • Net Charge

    • +3

    • Boman Index

    • -35.12

    • Hydrophobicity

    • -0.414

    • Aliphatic Index

    • 37.24

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 8605

    • Absorbance 280nm

    • 307.32

    • Polar Residues

    • 12

DRAMP02932

DRAMP02932 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Two novel antimicrobial peptides, arasin-likeSp and GRPSp, from the mud crab Scylla paramamosain, exhibit the activity against some crustacean pathogenic bacteria.

    • Reference

    • Fish Shellfish Immunol. 2011 Feb;30(2):706-712.

    • Author

    • Imjongjirak C, Amparyup P, Tassanakajon A.