General Information
-
DRAMP ID
- DRAMP03129
-
Peptide Name
- Cecropin-B2 (Insects, animals)
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Source
- Culex pipiens pipiens (Northern house mosquito)
-
Family
- Not found
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Gene
- CECB2
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Sequence
- GRSKKLGKKIEKAGKRVFNAAQKGLPVAAGVQAL
-
Sequence Length
- 34
-
UniProt Entry
- Q86PR4
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP03129.
Physicochemical Information
-
Formula
- C157H276N50O41
Absent Amino Acids
- CDHMTWY
Common Amino Acids
- K
Mass
- 3520.23
PI
- 11.3
Basic Residues
- 9
Acidic Residues
- 1
Hydrophobic Residues
- 14
Net Charge
- +8
-
Boman Index
- -46.28
Hydrophobicity
- -0.371
Aliphatic Index
- 89.12
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 7
DRAMP03129
Comments Information
Function
- Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria (By similarity).
Literature Information
- ·Literature 1
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Title
- Innate immunity in the Culex pipiens-Wuchereria bancrofti host-parasite relationship
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Pubmed ID
- PubMed ID is not available
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Reference
- Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
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Author
- Bartholomay L.C, Farid H.A, Ramzy R.M, Christensen B.M.