General Information

    • DRAMP ID

    • DRAMP03146

    • Peptide Name

    • Defensin

    • Source

    • Culex pipiens pipiens (Northern house mosquito)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ATCDLLSGFGVNDSACAAHCILRGNRGGYCNGKKVCVCRN

    • Sequence Length

    • 40

    • Protein Existence

    • Transcript level

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03146 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03146.

Physicochemical Information

    • Formula

    • C169H277N57O53S6

    • Absent Amino Acids

    • EMPQW

    • Common Amino Acids

    • CG

    • Mass

    • 4147.77

    • PI

    • 8.68

    • Basic Residues

    • 6

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +4

    • Boman Index

    • -58.69

    • Hydrophobicity

    • 0.05

    • Aliphatic Index

    • 70.75

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1865

    • Absorbance 280nm

    • 47.82

    • Polar Residues

    • 20

DRAMP03146

DRAMP03146 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Culex pipiens pipiens: characterization of immune peptides and the influence of immune activation on development of Wuchereria bancrofti.

    • Reference

    • Mol Biochem Parasitol. 2003 Aug 11;130(1):43-50.

    • Author

    • tholomay LC, Farid HA, Ramzy RM, Christensen BM.