General Information

    • DRAMP ID

    • DRAMP03361

    • Peptide Name

    • CRS4C-3a (Cryptdin related sequence peptide; Rodents, mammals, animals)

    • Source

    • Mus musculus (Mouse)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • LQDAALGWGRRCPRCPRCPNCRRCPRCPTCPSCNCNPK

    • Sequence Length

    • 38

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03361 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03361.

Physicochemical Information

    • Formula

    • C171H283N65O47S9

    • Absent Amino Acids

    • EFHIMVY

    • Common Amino Acids

    • C

    • Mass

    • 4290.08

    • PI

    • 9.27

    • Basic Residues

    • 8

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +7

    • Boman Index

    • -120.95

    • Hydrophobicity

    • -0.884

    • Aliphatic Index

    • 25.79

    • Half Life

      • Mammalian:5.5 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 6000

    • Absorbance 280nm

    • 162.16

    • Polar Residues

    • 16

DRAMP03361

DRAMP03361 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Increased diversity of intestinal antimicrobial peptides by covalent dimer formation.

    • Reference

    • Nat Immunol. 2004 Aug;5(8):836-843.

    • Author

    • Hornef M.W, Putsep K, Karlsson J, Refai E, Andersson M.