General Information

    • DRAMP ID

    • DRAMP03491

    • Peptide Name

    • Viresin (Insects, animals)

    • Source

    • Heliothis virescens (Tobacco budworm moth)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • YDNVNLDEILANDRLLVPYIKCLLDEGKKAPDAKELKEHIRXAL

    • Sequence Length

    • 44

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-

    • Target Organism

      • Gram-negative bacteria:
        Target OrganismActivity
        E. coli K12 D31-
        E. coli and E. cloacae-

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03491 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03491.

Physicochemical Information

    • Formula

    • C221H361N59O66S

    • Absent Amino Acids

    • FMQSTW

    • Common Amino Acids

    • L

    • Mass

    • 5062.06

    • PI

    • 5.12

    • Basic Residues

    • 8

    • Acidic Residues

    • 9

    • Hydrophobic Residues

    • 17

    • Net Charge

    • -1

    • Boman Index

    • -81.63

    • Hydrophobicity

    • -0.407

    • Aliphatic Index

    • 119.77

    • Half Life

      • Mammalian:2.8 hour
      • Yeast:10 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 2980

    • Absorbance 280nm

    • 69.3

    • Polar Residues

    • 7

DRAMP03491

DRAMP03491 chydropathy plot

Comments Information

    • Function

    • Has antibacterial activity against the Gram-negative bacteria E. coli and E. cloacae, but not against the Gram-negative bacteria P. aeruginosa, P. vulgaris, K. pneumoniae and S. enteritidis or the Gram-positive bacteria S. aureus, S. epidermidis and S. salivarius.

Literature Information

  • ·Literature 1

    • Title

    • Viresin. A novel antibacterial protein from immune hemolymph of Heliothis virescens pupae.

    • Reference

    • Eur J Biochem. 2000 Feb;267(3):677-683.

    • Author

    • Viresin. A novel antibacterial protein from immune hemolymph of Heliothis virescens pupae.