General Information
-
DRAMP ID
- DRAMP03538
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Peptide Name
- Cecropin (Antibacterial peptide CM-IV; Insects, animals)
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Source
- Bombyx mori (Silk moth)
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Family
- Belongs to the cecropin family
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Gene
- Not found
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Sequence
- RWKIFKKIEKVGQNIRDGIVKAGPAVAVVGQAATI
-
Sequence Length
- 35
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UniProt Entry
- P14666
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Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP03538.
Physicochemical Information
-
Formula
- C172H290N50O44
Absent Amino Acids
- CHLMSY
Common Amino Acids
- AIKV
Mass
- 3762.5
PI
- 10.56
Basic Residues
- 7
Acidic Residues
- 2
Hydrophobic Residues
- 17
Net Charge
- +5
-
Boman Index
- -30.49
Hydrophobicity
- 0.129
Aliphatic Index
- 111.43
Half Life
-
- Mammalian:1 hour
- Yeast:2 min
- E.coli:2 min
Extinction Coefficient Cystines
- 5500
Absorbance 280nm
- 161.76
Polar Residues
- 6
DRAMP03538
Comments Information
Function
- Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
Literature Information
- ·Literature 1
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Title
- Cell-free immunity in insects.
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Pubmed ID
- 3318666
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Reference
- Annu Rev Microbiol. 1987;41:103-126.
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Author
- Boman HG, Hultmark D.