General Information

    • DRAMP ID

    • DRAMP03959

    • Peptide Name

    • CGA41-70 (hrVS-1-derived peptide)

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • TLRGDERILSILRHQNLLKELQDLALQGAK

    • Sequence Length

    • 30

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Neurospora crassa (MIC=7 µM), Alternaria brassicicola (MIC=7 µM), Nectria haematococca (MIC=7 µM), Fusarium culmorum (MIC=10 µM), F. oxyporum (MIC=30 µM), Trichophyton mentagrophytes (MIC=30 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03959 helical wheel diagram

    • Predicted Structure

    • There is no predicted structure for DRAMP03959.

Physicochemical Information

    • Formula

    • C150H261N47O45

    • Absent Amino Acids

    • CFMPVWY

    • Common Amino Acids

    • L

    • Mass

    • 3443.01

    • PI

    • 8.29

    • Basic Residues

    • 6

    • Acidic Residues

    • 4

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +2

    • Boman Index

    • -66.11

    • Hydrophobicity

    • -0.393

    • Aliphatic Index

    • 136.67

    • Half Life

      • Mammalian:7.2 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP03959

DRAMP03959 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A.

    • Reference

    • J Biol Chem. 2000 Apr 14;275(15):10745-10753.

    • Author

    • Lugardon K, Raffner R, Goumon Y, Corti A, Delmas A, Bulet P, Aunis D, Metz-Boutigue MH.