General Information

    • DRAMP ID

    • DRAMP04347

    • Peptide Name

    • Buforin

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RAGLQFPVGRLLRRLLRRLLR

    • Sequence Length

    • 21

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04347 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04347.

Physicochemical Information

    • Formula

    • C115H207N43O23

    • Absent Amino Acids

    • CDEHIKMNSTWY

    • Common Amino Acids

    • LR

    • Mass

    • 2560.18

    • PI

    • 12.78

    • Basic Residues

    • 7

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +7

    • Boman Index

    • -64.83

    • Hydrophobicity

    • -0.095

    • Aliphatic Index

    • 148.57

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 2

DRAMP04347

DRAMP04347 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Mechanism of action and specificity of antimicrobial peptides designed based on buforin IIb.

    • Reference

    • Peptides. 2012 Apr;34(2):283-289.

    • Author

    • Jang SA, Kim H, Lee JY, Shin JR, Kim da J, Cho JH, Kim SC.