General Information

    • DRAMP ID

    • DRAMP04565

    • Peptide Name

    • Laticeptin

    • Source

    • Leptodatylus laticeps

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GVVDILKGAAKDLAGHLATKVMNKL

    • Sequence Length

    • 25

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04565 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04565.

Physicochemical Information

    • Formula

    • C114H200N32O32S

    • Absent Amino Acids

    • CEFPQRSWY

    • Common Amino Acids

    • AKL

    • Mass

    • 2563.1

    • PI

    • 9.53

    • Basic Residues

    • 5

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +3

    • Boman Index

    • -4.38

    • Hydrophobicity

    • 0.408

    • Aliphatic Index

    • 128.8

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP04565

DRAMP04565 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Purification and properties of laticeptin, an antimicrobial peptide from skin secretions of the South American frog Leptodactylus laticeps.

    • Reference

    • Protein Pept Lett. 2006;13(4):411-415.

    • Author

    • Conlon JM, Al-Ghaferi N, Abraham B, Sonnevend A, King JD, Nielsen PF.