Patent Information

    • DRAMP ID

    • DRAMP04837

    • Sequence

    • KGWGSFFKKAAHVGKHVGKAALTHYL

    • Sequence Length

    • 26

    • Sequence Name

    • Sequence 15 from Patent US 20030096949

    • Source

    • Synthetic construct

    • Activity

    • Antimicrobial, Antibacterial

    • Patent Type

    • Patent Application

    • Publication Date

    • 2003-5-22

    • Patent Title

    • Anti-endotoxic antimicrobial cationic peptides and methods of use therfor.

    • Abstract

    • A novel class of cationic peptides having antimicrobial activity is provided. Exemplary peptides of the invention include KWKSFIKKLTSAAKKVVTTAKPLALIS (SEQ ID NO:3) and KGWGSFFKKAAHVGKHVGKAALTHYL (SEQ ID NO:15). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. Such methods are useful for the treatment of respiratory infections, such as in cystic fibrosis patients. Such methods are further useful for accelerating wound healing.