Patent Information

    • DRAMP ID

    • DRAMP17459

    • Sequence

    • WYAXFEXLLR

    • Sequence Length

    • 10

    • Sequence Name

    • Sequence 85 from Patent US 20120328692

    • Source

    • Synthetic construct

    • Activity

    • Anticancer

    • Patent Type

    • Patent Application

    • Publication Date

    • 2012-12-27

    • Patent Title

    • Potent D-peptide antagonists of mdm2 and mdmx for anticancer therapy.

    • Abstract

    • The present invention relates to a group of MDM2 and MDMX antagonists, namely, D-peptides, variants thereof, and stapled D-peptides, along with pharmaceutical compositions comprising the antagonists, and methods of treating conditions such as cancer using the antagonists.