• DRAMP ID

    • DRAMP18120
    • Peptide Name

    • BnPRP1 (Plant defensin)
    • Source

    • Brassica napus
    • Family

    • Gene

    • BnPRP1
    • Sequence

    • PPTQNPSMAPPTQNPYGQPMTPPTQNPYGQPMAPP
    • Sequence Length

    • 35
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Biological Activity

    • Antibacterial, Antifugal, Anti-Gram+, Anti-Gram-, Antimicrobial
    • Target Organism

      • Gram-positive: M. luteus (MIC= 16.9 ± 2.7 uM );
      • Gram-negative: E. coli (MIC= 8.4 ± 1.4 uM);
      • Fungi:Sclerotinia sclerotiorum, Mucor sp., Magnaporthe oryzae and Botrytis cinerea
    • Hemolytic Activity

      • N/A
    • Cytotoxicity

    • Binding Target

    • N/A
    • Linear/Cyclic/Branched

    • N-terminal modification

    • C-terminal modification

    • Other modifications

    • Stereochemistry

    • Structure

    • N/A
    • Structure Description

    • N/A
    • DRAMP18120 helical wheel diagram
    • Formula

    • C164H245N43O51S3
    • Absent Amino Acids

    • CDEFHIKLRVW
    • Common Amino Acids

    • P
    • Mass

    • 433778
    • PI

    • 6.09
    • Basic Residues

    • 0
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 2
    • Boman Index

    • -4903
    • Hydrophobicity

    • -132.86
    • Aliphatic Index

    • 5.71
    • Half Life

      • Mammalian:>20 hour
      • Yeast:>20 hour
      • E.coli:?
    • Extinction Coefficient Cystines

    • 2980
    • Absorbance 280nm

    • 87.65
    • Polar Residues

    • 12

DRAMP18120

DRAMP18120 chydropathy plot
    • BnPRP1 has 40.5% identity with a known proline-rich antimicrobial peptide SP-B from the pig. BnPRP1 isolated from B. napus was the first PR-AMP member that was characterized in plants, and its homology sequences were found in some other Brassicaceae plants by the genome sequences analysis.

  • Literature 1
    • Reference

    • PLoS One. 2015 Sep 18;10(9):e0137414.
    • Author

    • Cao H, Ke T, Liu R, et al.
    • Title

    • Identification of a Novel Proline-Rich Antimicrobial Peptide from Brassica napus.