• DRAMP ID

    • DRAMP18199
    • Peptide Name

    • Formicin (Bacteriocin;lantibiotic;Gram-positive bacteria, prokaryotes; U
    • Source

    • Bacillus paralicheniformis APC 1576
    • Family

    • Belongs to the lantibiotic family (Class I bacteriocin)
    • Gene

    • Unknow
    • Sequence

    • CEWYNISCQLGNKGQWCTLTKECQRSCK
    • Sequence Length

    • 28
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Biological Activity

    • Anti-Gram+
    • Target Organism

      • No MICs found on DRAMP database
    • Hemolytic activity

    • Unknown
    • Binding Traget

    • Unknow
    • Structure

    • Unknow
    • Structure Description

    • Unknow
    • PDB ID

    • Unknow
    • DRAMP18199 helical wheel diagram
    • Formula

    • C139H217N41O43S5
    • Absent Amino Acids

    • ADFHMPV
    • Common Amino Acids

    • C
    • Mass

    • 379259
    • PI

    • 8.21
    • Basic Residues

    • 4
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 5
    • Boman Index

    • -5947
    • Hydrophobicity

    • -82.14
    • Aliphatic Index

    • 41.79
    • Half Life

      • Mammalian:1.2 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 12740
    • Absorbance 280nm

    • 471.85
    • Polar Residues

    • 14

DRAMP18199

DRAMP18199 chydropathy plot
    • Function

    • Active against a broad spectrum of Gram+ bacteria (e.g., L. s delbrueckii subsp. bulgaricus; L. amylophilus; L. lactis; M. luteus; S. smutans), including clinical strains S. aureus, C. difficile, and L. monocytogenes.
  • Literature 1
    • Reference

    • Microbiology. 162(9):1662-1671(2016)
    • Author

    • Collins FW, O'Connor PM, O'Sullivan O, Rea MC, Hill C, Ross RP
    • Title

    • Formicin - a novel broad-spectrum two-component lantibiotic produced by Bacillus paralicheniformis APC 1576.