General Information
-
DRAMP ID
- DRAMP18202
-
Peptide Name
- WB Piscidin 5 (fish, animals)
-
Source
- Morone chrysops
-
Family
- Belongs to the defensin family
-
Gene
- Not found
-
Sequence
- LIGSLFRGAKAIFRGARQGWRSHKAVSRYRARYVRRPVIYYHRVYP
-
Sequence Length
- 46
-
Swiss_Prot Entry
- E3UVF7(Precursor)
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Evidence code
Activity Information
-
Biological Activity
- Anti-Gram+ & Gram-, Antiparasitic
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Target Organism
- Staphylococcus aureus ATCC 29213(MIC 4.52uM)
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Hemolytic Activity
-
- Not found
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Cytotoxicity
-
- Not included yet
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Binding Target
- Lipid-binding
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Other Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
PDB ID
- None
-
-
Physicochemical Information
-
Formula
- C255H398N84O56
Absent Amino Acids
- CDEMNT
Common Amino Acids
- R
Mass
- 633930
PI
- 12.34
Basic Residues
- 14
Acidic Residues
- 0
Hydrophobic Residues
- 17
-
Boman Index
- -12420
Hydrophobicity
- -0.539
Aliphatic Index
- 78.48
Half Life
-
- Mammalian:5.5 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 12950
Absorbance 280nm
- 287.78
Polar Residues
- 12
DRAMP18202

Comments Information
No more comments
Literature Information
- ·Literature 1
-
Title
- A Diverse Family of Host-Defense Peptides (Piscidins) Exhibit Specialized Anti-Bacterial and Anti-Protozoal Activities in Fishes.
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Pubmed ID
- 27552222
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Reference
- PLoS One. 11(8):e0159423(2016)
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Author
- Salger SA, Cassady KR, Reading BJ, Noga EJ