• DRAMP ID

    • DRAMP18203
    • Peptide Name

    • Panusin (beta defensins; crustaceans, arthropods, invertebrates, animals; XXA; UCSS1a)
    • Source

    • the Caribbean spiny lobster, Panulirus genus
    • Family

    • Belongs to the beta-defensin family
    • Gene

    • Unknow
    • Sequence

    • SYVGDCGSNGGSCVSSYCPYGNRLNYFCPLGRTCCRRSY
    • Sequence Length

    • 39
    • Evidence code

    • Biological Activity

    • Anti-Gram+ & Gram-, Antifungal
    • Target Organism

      • No MICs found on DRAMP database
    • Hemolytic activity

    • Unknown
    • Binding Traget

    • Lipid-binding
    • Structure

    • Unknow
    • Structure Description

    • Unknow
    • PDB ID

    • Unknow
    • DRAMP18203 helical wheel diagram
    • Formula

    • C178H266N54O57S6
    • Absent Amino Acids

    • AEHIKMQW
    • Common Amino Acids

    • CGS
    • Mass

    • 494471
    • PI

    • 8.37
    • Basic Residues

    • 4
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 5
    • Boman Index

    • -7777
    • Hydrophobicity

    • -40.51
    • Aliphatic Index

    • 34.87
    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 7825
    • Absorbance 280nm

    • 205.92
    • Polar Residues

    • 27

Amino Acid Distribution

DRAMP18203 chydropathy plot
    • Function

    • Active against E. coli, K. pneumonia, S. aureus, B. subtilisspizizenii, and C. albicans.
  • Literature 1
    • Reference

    • Dev Comp Immunol. pii: S0145-305X(16)30274-9(2016)
    • Author

    • Montero-Alejo V, Corzo G, Porro-Suard
    • Title

    • Panusin represents a new family of beta-defensin-like peptides in invertebrates.