• DRAMP ID

    • DRAMP18362
    • Peptide Name

    • Formicin (bacteriocin)
    • Source

    • Bacillus paralicheniformis APC 1576
    • Family

    • Belongs to the lantibiotic family.
    • Gene

    • Not found
    • Sequence

    • CEWYNISCQLGNKGQWCTLTKECQRSCK
    • Sequence Length

    • 28
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

      • Gram-positive bacteria: L. s delbrueckii subsp. bulgaricus, L. amylophilus, L. lactis, M. luteus, S. smutans, including clinical strains S. aureus, C. difficile, and L. monocytogenes.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP18362 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP18362.
    • Formula

    • C139H217N41O43S5
    • Absent Amino Acids

    • ADFHMPV
    • Common Amino Acids

    • C
    • Mass

    • 3310.8
    • PI

    • 8.4
    • Basic Residues

    • 4
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 5
    • Net Charge

    • +2
    • Boman Index

    • -5947
    • Hydrophobicity

    • -0.821
    • Aliphatic Index

    • 41.79
    • Half Life

      • Mammalian:1.2 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 12740
    • Absorbance 280nm

    • 471.85
    • Polar Residues

    • 14

DRAMP18362

DRAMP18362 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Formicin - a novel broad-spectrum two-component lantibiotic produced by Bacillus paralicheniformis APC 1576
    • Reference

    • Microbiology. 2016 Sep;162(9):1662-1671.
    • Author

    • Collins FW, O'Connor PM, O'Sullivan O, Rea MC, Hill C, Ross RP.