Patent Information

    • DRAMP ID

    • DRAMP18831

    • Sequence

    • MEHFRWG

    • Sequence Length

    • 7

    • Sequence Name

    • Sequence 1 from Patent US 7244710

    • Source

    • Homo sapiens

    • Activity

    • Antimicrobial, Antibacterial, Antifungal

    • Patent Type

    • Granted Patent

    • Publication Date

    • 2007-7-17

    • Patent Title

    • Treatment Of Ophthalmic Infections Using Antimicrobial Peptides

    • Abstract

    • The present invention discloses a method of treating an ophthalmic infection by administering to a vertebrate inflicted with the ophthalmic infection an ophthalmologically effective amount of an antimicrobial peptide which is derived from alpha-melanocyte-stimulating hormone (alpha-MSH) and biologically functional equivalents thereof. Specifically, the antimicrobial peptides derived from alpha-melanocyte-stimulating hormone (alpha-MSH) include alpha-MSH (1-13) which is SYSMEHFRWGKPV, alpha-MSH (4-10) which is MEHFRWG, alpha-MSH (6-13) which is HFRWGKPV, alpha-MSH (11-13) which is KPV, and a KPV dimer. The ophthalmic infection can be caused by a microorganism which include a bacteria, a fungi or a virus. The vertebrate includes a bird and a mammal. The antimicrobial peptide has anti-bacterial, antifungal, and antiviral property and therefore can be administered at the onset of the ophthalmic infection before the microorganism causing the infection is determined as well as thereafter.