Patent Information

    • DRAMP ID

    • DRAMP19020

    • Sequence

    • GWGSFFKKAAHVGKHVGKAALGAAARRRK

    • Sequence Length

    • 29

    • Sequence Name

    • Sequence 19 from Patent US 6818407

    • Source

    • Synthetic construct

    • Activity

    • Antimicrobial, Antibacterial, Antifungal

    • Patent Type

    • Granted Patent

    • Publication Date

    • 2004-11-16

    • Patent Title

    • Antiendotoxic Antimicrobial Cationic Peptides And Methods Of Use Therfor

    • Abstract

    • A novel class of cationic peptides having antimicrobial activity is provided. Exemplary peptides of the invention include KWKSFIKKLTSAAKKVVTTAKPLALIS (SEQ ID NO,3) and KGWGSFFKKAAHVGKHVGKAALTHYL (SEQ ID NO,18). Also provided are methods for inhibiting therowth of bacteria utilizing the peptides of the invention. Such methods are useful for the treatment of respiratory infections, such as in cystic fibrosis patients. Such methods are further useful for accelerating wound healing.