General Information
-
DRAMP ID
- DRAMP20795
-
Peptide Name
- So-D1 (S. oleracea defensin 1; spinach defensins, plants)
-
Source
- Spinacia oleracea (Spinach)
-
Family
- Belongs to the DEFL family. Group II subfamily.
-
Gene
- Not found
-
Sequence
- XTCESPSHKFKGPCATNRNCES
-
Sequence Length
- 22
-
UniProt Entry
- P81572
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
-
Target Organism
-
- [Ref.9762899] Gram-positive bacterium: Clavibacter michiganensis (EC50=1 μM);
- Gram-negative bacterium: Ralstonia solanacearum (EC50=15 μM).
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
- No cytotoxicity information found in the reference(s) presented
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Linear
-
N-terminal Modification
- Free
-
C-terminal Modification
- Free
-
Nonterminal Modifications and Unusual Amino Acids
- None
-
Stereochemistry
- L
-
Structure
- Bridge
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP20795.
Physicochemical Information
-
Formula
Absent Amino Acids
Common Amino Acids
Mass
- 2407.86
PI
- 7.96
Basic Residues
Acidic Residues
Hydrophobic Residues
Net Charge
-
Boman Index
- 0
Hydrophobicity
- 0
Aliphatic Index
- 0
Half Life
-
- Mammalian:
- Yeast:
- E.coli:
Extinction Coefficient Cystines
Absorbance 280nm
- 0
Polar Residues
DRAMP20795
Comments Information
Function
- Antimicrobial peptide. Active against Gram-positive and Gram-negative bacteria pathogens.
Literature Information
- ·Literature 1
-
Title
- Novel defensin subfamily from spinach (Spinacia oleracea).
-
Pubmed ID
- 9762899
-
Reference
- FEBS Lett. 1998 Sep 18;435(2-3): 159-162.
-
Author
- Segura A, Moreno M, Molina A, Garcia-Olmedo F