Patent Information

    • DRAMP ID

    • DRAMP27723

    • Sequence

    • RSYMECYEQASRKGNRSIRR

    • Sequence Length

    • 20

    • Sequence Name

    • Sequence 67 from Patent US 20190279741

    • Source

    • Synthetic construct

    • Activity

    • Antimicrobial, Antibacterial

    • Patent Type

    • Patent Application

    • Publication Date

    • 2020-9-12

    • Patent Title

    • Computational Platform For In Silico Combinatorial Sequence Space Exploration And Artificial Evolution Of Peptides

    • Abstract

    • Disclosed herein are methods of designing peptides having at least one property of interest, such as α-helical propensity, higher net charge, hydrophobicity, and/or hydrophobic moment. Also disclosed herein are novel artificially evolved peptides (e.g., antimicrobial peptides), which may be designed according to the methods described herein, and methods of use thereof.