Patent Information

    • DRAMP ID

    • DRAMP28879

    • Sequence

    • XXXKXXKKXKKXXKXXXKXXKK

    • Sequence Length

    • 22

    • Sequence Name

    • Sequence 259 from Patent US 10464975

    • Source

    • Synthetic construct

    • Activity

    • Antimicrobial

    • Patent Type

    • Granted Patent

    • Publication Date

    • 2019-11-5

    • Patent Title

    • Stabilized Anti-microbial Peptides

    • Abstract

    • The present invention provides methods of designing and making structurally stabilized anti-microbial peptides for the prophylaxis and treatment of infection. Methods are also disclosed for designing stabilized anti-microbial peptides that are selectively lytic/cytotoxic to bacteria, allowing for internal use of anti-microbial peptides without mammalian membrane disruption and cytotoxicity.