• • DRAMP ID

  • DRAMP33144

• • Peptide Name

  • Decoralin [AT4]

• • Source

  • Synthetic (Derived from Decoralin)

• • Family

• • Gene

  • Not found

• • Sequence

  • LLLLLIRKLIL

• • Sequence Length

  • 11

• • UniProt Entry

  • Notavailable

• • Protein Existence

  • Not found

• • SMILES

  • CC[C@@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)[C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(N)=O

• • Biological Activity

  • Antimicrobial, Anticancer

• • Target Organism

  • • Tumor cells:

      Target Organism	Activity
      MCF-7 (EC50=25±1 μM); 1205Lu (EC50=48±1 μM); Jurkat (EC50=50±1 μM); A549	EC50>100 μM

• • Hemolytic Activity

  • • Not available

• • Cytotoxicity

  • • HDMEC: EC50=278±1 μM

• • Binding Target

  • Not available

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

  • Notavailable

• Predicted Structure

• There is no predicted structure for DRAMP33144.

DRAMP33144

• • Not available

• ·Literature 1

• • Title

  • Multidimensional Design of Anticancer Peptides

• • Pubmed ID

  • 26119906

• • Reference

  • Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-4.

• • Author

  • Lin YC, Lim YF, Russo E, Schneider P, Bolliger L, Edenharter A, Altmann KH, Halin C, Hiss JA, Schneider G.