Result: 1 - 20 of 74
DRAMP IDNAMEDescriptionMedical_useStage of developmentCompany
DRAMP18057MSI-78(Pexiganan)a broad-spectrum synthetic analogue of the African frog peptide magaininimpetigoPhase III(Failure)Genaera (Plymouth, PA)
DRAMP18058MSI-78(Pexiganan)a broad-spectrum synthetic analogue of the African frog peptide magainintreatment of diabetic foot ulcersPhase III(denied approval for use in 1999Genaera (Plymouth, PA)
DRAMP18059Iseganan(IB-367)a synthetic analogue of Protegrin I (IBL-367),extracted from porcine leukocytes;the pig protegrin derivativea mouth rinse to prevent polymicrobial infection associated with oral mucositis in patients receiving chemotherapyPhase III(Failure)Intrabiotics Pharmaceuticals Inc.(Mountain View, CA)
DRAMP18060Iseganan(IB-367)a synthetic analogue of Protegrin I (IBL-367),extracted from porcine leukocytes;the pig protegrin derivativean aerosolized treatment for ventilator-associated pneumoniaPhase III(Failure)Intrabiotics Pharmaceuticals Inc.(Mountain View, CA)
DRAMP18061Histatinusing a variant of histatins, which are naturally occurring cationic peptides in salivaantimicrobial-peptide-containing mouth wash for the treatment of oral candidiasis (gingivitis and periodontal diseases)Phase II-IIIDemgen and Dow Pharmaceutical Sciences;licensed to the Vancouver, Canada, company Pacgen
DRAMP18062Histatinusing a variant of histatins, which are naturally occurring cationic peptides in salivachronic Pseudomonas aeruginosa infectionsPhase IDemgen and Dow Pharmaceutical Sciences;licensed to the Vancouver, Canada, company Pacgen
DRAMP18063P113a 12 amino acid fragment of histatin 5HIVPhase II(Completed)Demgen
DRAMP18064P113Da 12 amino acid fragment of histatin 5an inhalation treatment for Pseudomonas aeruginosainfections in cystic fibrosis patientsUnknowDemgen
DRAMP18065MBI-226(Omiganin)Synthetic 12-mer cationic peptide derived from indolicidinthe treatment of catheter-related infectionsPhase IIIb(Failure)Migenix (Vancouver, BritishColumbia, Canada)
DRAMP18066MBI peptides as Omiganan(particularly MBI-226 and Manalogues of indolicidinacne and chronic nasal carrier of S. aureusPhase II(Failure)Migenix (Vancouver, BritishColumbia, Canada)
DRAMP18067MX-594ANIndolicidin basedthe treatment of catheter-related acnePhase IIb(Completed)Migenix (Vancouver, BritishColumbia, Canada)
DRAMP18068hLF1-11an 11-mer peptide from the N terminus of human lactoferrinLPS-mediated diseasesand fungal infectionsPhase I(Completed)AM-Pharma Holding BV
DRAMP18069rBPI21(Neuprex)a human bactericidal permeability protein derivativemeningococcaemia;prophylactic treatment of infectious complications from post-traumatic bleeding (in 842 patients)Phase III(Failure)Xoma Ltd(Berkeley, CA, USA)
DRAMP18070XMP 629extracted from humanAcnePhase IIIXoma Ltd(Berkeley, CA, USA)
DRAMP18071Mycoprexextracted from insectsFungal infectionsPhase IIIXoma Ltd.
DRAMP18072Heliomocin variants(ETD151)an antifungal 44 amino acid peptide, variant of a natural peptide from lepidopteran Heliothis virescensSystemic fungal infections in immunocompromised patients and multi-resistant bacterial infections PreclinicalEntoMed SA
DRAMP18073PG-1Protegrin ClassTreatment of peritoneal infections caused by P. aeruginosa and S. aureus.Treatment of pneumoniaUnknowIntrabiotics
DRAMP18074CSA-13cationic steroid (ceragenin) that mimics host-defense peptidesAnti-infectivePreclinicalCeragenix(Denver)
DRAMP18075HB-50synthetic natural peptide mimetic of cecropinAnti-infectivePreclinicalHelix Biomedix(Bothell, Washington, USA)
DRAMP18076HB-10719-amino-acid fragment of cecropin BWound healingPreclinicalHelix Biomedix(Bothell, Washington, USA)
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